ACD10 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q6JQN1 |
| Other Accession | NP_079523.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 118834 Da |
| Antigen Region | 393-421 aa |
| Gene ID | 80724 |
|---|---|
| Other Names | Acyl-CoA dehydrogenase family member 10, ACAD-10, 1399-, ACAD10 |
| Target/Specificity | This ACD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-421 amino acids from the Central region of human ACD10. |
| Dilution | FC~~1:10~50 IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ACD10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ACAD10 |
|---|---|
| Function | Acyl-CoA dehydrogenase only active with R- and S-2-methyl- C15-CoA. |
| Tissue Location | Widely expressed with highest expression in fetal brain, followed by heart, muscle, kidney and adult brain. Expression levels varying from isoform to isoform. |

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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
References
Bian, L., et al. Diabetologia 53(7):1349-1353(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)
Ye, X., et al. Mol. Biol. Rep. 31(3):191-195(2004)
Sogayar, M.C., et al. Genome Res. 14(7):1413-1423(2004)
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