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EFHB Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q8N7U6 |
| Other Accession | NP_653316.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 93802 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 151651 |
|---|---|
| Other Names | EF-hand domain-containing family member B, EFHB |
| Target/Specificity | This EFHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human EFHB. |
| Dilution | FC~~1:10~50 IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | EFHB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EFHB (HGNC:26330) |
|---|---|
| Synonyms | CFAP21 |
| Function | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:36191189). Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion and the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus (PubMed:30481768). |
| Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q8CDU5}. Cytoplasm |
| Tissue Location | Expressed in airway epithelial cells. |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
EFHB contains two EF-hand domains. There are three named isoforms.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
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$ 150.00
$ 385.00
Cat# AP10904a
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