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NUSAP Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9BXS6 |
| Other Accession | NP_057443.2, NP_001123369.1, NP_060924.4 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 49452 Da |
| Antigen Region | 27-56 aa |
| Gene ID | 51203 |
|---|---|
| Other Names | Nucleolar and spindle-associated protein 1, NuSAP, NUSAP1, ANKT |
| Target/Specificity | This NUSAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-56 amino acids from the N-terminal region of human NUSAP. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NUSAP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NUSAP1 |
|---|---|
| Synonyms | ANKT |
| Function | Microtubule-associated protein with the capacity to bundle and stabilize microtubules (By similarity). May associate with chromosomes and promote the organization of mitotic spindle microtubules around them. |
| Cellular Location | Cytoplasm. Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle Chromosome. Note=Found in the cytoplasm and nucleolus during interphase and redistributes to the mitotic spindle in prometaphase (By similarity). Localizes to the mitotic spindle during anaphase and telophase then disappears from around the chromosomes during cytokinesis (By similarity). Localizes to multiple distinct regions of chromosomes throughout mitosis. {ECO:0000250, ECO:0000269|PubMed:17276916, ECO:0000269|PubMed:17618083} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
NUSAP1 is a nucleolar-spindle-associated protein that plays a role in spindle microtubule organization (Raemaekers et al., 2003 [PubMed 12963707]).
References
Wadia, P.P., et al. Blood 115(10):2077-2087(2010)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)
Raemaekers, T., et al. J. Cell Biol. 162(6):1017-1029(2003)
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