TM168 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, WB, E |
---|---|
Primary Accession | Q9H0V1 |
Other Accession | Q5PQM0, Q91VX9, NP_071929.3 |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 79755 Da |
Antigen Region | 558-587 aa |
Gene ID | 64418 |
---|---|
Other Names | Transmembrane protein 168, TMEM168 |
Target/Specificity | This TM168 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 558-587 amino acids from the C-terminal region of human TM168. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TM168 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TMEM168 (HGNC:25826) |
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Function | Plays a key role in maintaining the cardiac electrical stability by modulating cell surface expression of SCN5A (PubMed:32175648). May play a role in the modulation of anxiety behavior by regulating GABAergic neuronal system in the nucleus accumbens (By similarity). |
Cellular Location | Nucleus membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
TMEM168 is a multi-pass membrane protein. It belongs to the TMEM168 family. The exact function of TMEM168 remains unknown.
References
Trynka, G., et al. Gut (2009) In press :
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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