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ZC3H3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q8IXZ2 |
| Other Accession | Q8CHP0, NP_055932.2 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 101941 Da |
| Antigen Region | 920-948 aa |
| Gene ID | 23144 |
|---|---|
| Other Names | Zinc finger CCCH domain-containing protein 3, ZC3H3, KIAA0150, ZC3HDC3 |
| Target/Specificity | This ZC3H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 920-948 amino acids from the C-terminal region of human ZC3H3. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZC3H3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZC3H3 |
|---|---|
| Function | Required for the export of polyadenylated mRNAs from the nucleus (PubMed:19364924). Enhances ACVR1B-induced SMAD-dependent transcription. Binds to single-stranded DNA but not to double-stranded DNA in vitro. Involved in RNA cleavage (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q8CHP0}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Contains 5 C3H1 type zinc fingers.
References
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Hurt, J.A., et al. J. Cell Biol. 185(2):265-277(2009)
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