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KT33A Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O76009 |
| Other Accession | Q14525, O76011, Q15323, NP_004129.2 |
| Reactivity | Mouse |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 45940 Da |
| Antigen Region | 56-85 aa |
| Gene ID | 3883 |
|---|---|
| Other Names | Keratin, type I cuticular Ha3-I, Hair keratin, type I Ha3-I, Keratin-33A, K33A, KRT33A, HHA3-I, HKA3A, KRTHA3A |
| Target/Specificity | This KT33A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human KT33A. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KT33A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KRT33A |
|---|---|
| Synonyms | HHA3-I, HKA3A, KRTHA3A |
| Tissue Location | Expressed in the hair follicles. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B. [provided by RefSeq].
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
Rogers, M.A., et al. Differentiation 72 (9-10), 527-540 (2004) :
Langbein, L., et al. J. Biol. Chem. 274(28):19874-19884(1999)
Rogers, M.A., et al. J. Biol. Chem. 273(41):26683-26691(1998)
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