PRR19 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, WB, E |
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Primary Accession | A6NJB7 |
Other Accession | NP_954979.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 38716 Da |
Antigen Region | 208-236 aa |
Gene ID | 284338 |
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Other Names | Proline-rich protein 19, PRR19 |
Target/Specificity | This PRR19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-236 amino acids from the Central region of human PRR19. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PRR19 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PRR19 (HGNC:33728) |
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Function | Promotes meiotic crossing over formation through its interaction with CNTD1 by participating in the crossover differentiation step of crossover-specific recombination intermediates. |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:B2RW88}. Chromosome {ECO:0000250|UniProtKB:B2RW88}. Note=Co-localized at crossover sites with CNTD1. Localizes on synapsed chromosome only in mid/late pachytene spermatocytes. {ECO:0000250|UniProtKB:B2RW88} |
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Provided below are standard protocols that you may find useful for product applications.
Background
The specific function of PRR19 remains unknown. There are 2 isoforms produced by alternative splicing.
References
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
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