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PCDH1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, IHC-P, E |
|---|---|
| Primary Accession | Q08174 |
| Other Accession | NP_115796.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 114743 Da |
| Antigen Region | 179-206 aa |
| Gene ID | 5097 |
|---|---|
| Other Names | Protocadherin-1, Cadherin-like protein 1, Protocadherin-42, PC42, PCDH1 |
| Target/Specificity | This PCDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the N-terminal region of human PCDH1. |
| Dilution | WB~~1:1000 IF~~1:10~50 IHC-P~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PCDH1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PCDH1 |
|---|---|
| Function | May be involved in cell-cell interaction processes and in cell adhesion. |
| Cellular Location | Cell junction. Cell membrane; Single-pass type I membrane protein. Note=Found at cell- cell boundaries and probably at cell-matrix boundaries |
| Tissue Location | Highly expressed in the brain and neuro-glial cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.
References
Koppelman, G.H., et al. Am. J. Respir. Crit. Care Med. 180(10):929-935(2009)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
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