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FAM109A Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q8N4B1 |
| Other Accession | NP_653272.2, NP_001171468.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 27215 Da |
| Antigen Region | 3-31 aa |
| Gene ID | 144717 |
|---|---|
| Other Names | Sesquipedalian-1, Ses1, 27 kDa inositol polyphosphate phosphatase-interacting protein A, IPIP27A, FAM109A |
| Target/Specificity | This FAM109A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-31 amino acids from the N-terminal region of human FAM109A. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FAM109A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PHETA1 (HGNC:26509) |
|---|---|
| Function | Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane. |
| Cellular Location | Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Interaction with OCRL may be crucial for targeting to endosome and to the trans- Golgi network. Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein that localizes to the endosome and interacts with the enzyme, inositol polyphosphate 5-phosphatase OCRL-1. Alternate splicing results in multiple transcript variants.
References
Swan, L.E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(8):3511-3516(2010)
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