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STXBP3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | O00186 |
| Other Accession | NP_009200.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 67764 Da |
| Antigen Region | 145-171 aa |
| Gene ID | 6814 |
|---|---|
| Other Names | Syntaxin-binding protein 3, Platelet Sec1 protein, PSP, Protein unc-18 homolog 3, Unc18-3, Protein unc-18 homolog C, Unc-18C, STXBP3 |
| Target/Specificity | This STXBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-171 amino acids from the Central region of human STXBP3. |
| Dilution | IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | STXBP3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | STXBP3 |
|---|---|
| Function | Together with STX4 and VAMP2, may play a role in insulin- dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. |
| Cellular Location | Cytoplasm, cytosol. Cell membrane. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated |
| Tissue Location | Megakaryocytes and platelets. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Together with STX4 and VAMP2, STXBP3 may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity).
References
Bostrom, P., et al. Diabetes 59(8):1870-1878(2010)
Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
Brochetta, C., et al. Biochim. Biophys. Acta 1783(10):1781-1791(2008)
Smithers, N.P., et al. J. Recept. Signal Transduct. Res. 28(6):581-589(2008)
Fu, J., et al. J. Biol. Chem. 280(5):3178-3184(2005)
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