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STXBP3 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - STXBP3 Antibody (Center) AP12470c
    STXBP3 Antibody (Center) (Cat. #AP12470c) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the STXBP3 antibody detected the STXBP3 protein (arrow).
    detail
  • IHC-P - STXBP3 Antibody (Center) AP12470c
    STXBP3 Antibody (Center) (Cat. #AP12470c)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STXBP3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession O00186
Other Accession NP_009200.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 67764 Da
Antigen Region 145-171 aa
Additional Information
Gene ID 6814
Other Names Syntaxin-binding protein 3, Platelet Sec1 protein, PSP, Protein unc-18 homolog 3, Unc18-3, Protein unc-18 homolog C, Unc-18C, STXBP3
Target/Specificity This STXBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-171 amino acids from the Central region of human STXBP3.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSTXBP3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STXBP3
Function Together with STX4 and VAMP2, may play a role in insulin- dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Cellular Location Cytoplasm, cytosol. Cell membrane. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated
Tissue Location Megakaryocytes and platelets.
Research Areas
Citations (0)
citation

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Background

Together with STX4 and VAMP2, STXBP3 may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity).

References

Bostrom, P., et al. Diabetes 59(8):1870-1878(2010)
Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
Brochetta, C., et al. Biochim. Biophys. Acta 1783(10):1781-1791(2008)
Smithers, N.P., et al. J. Recept. Signal Transduct. Res. 28(6):581-589(2008)
Fu, J., et al. J. Biol. Chem. 280(5):3178-3184(2005)

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$ 182.50
$ 70.00
Cat# AP12470c
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