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CA6 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CA6 Antibody (C-term) AP12663b
    CA6 Antibody (C-term) (Cat. #AP12663b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CA6 antibody detected the CA6 protein (arrow).
    detail
  • IHC-P - CA6 Antibody (C-term) AP12663b
    CA6 Antibody (C-term) (Cat. #AP12663b)immunohistochemistry analysis in formalin fixed and paraffin embedded human melanoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CA6 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession P23280
Other Accession NP_001206.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 35367 Da
Antigen Region 238-267 aa
Additional Information
Gene ID 765
Other Names Carbonic anhydrase 6, Carbonate dehydratase VI, Carbonic anhydrase VI, CA-VI, Salivary carbonic anhydrase, Secreted carbonic anhydrase, CA6
Target/Specificity This CA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-267 amino acids from the C-terminal region of human CA6.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCA6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CA6
Function Reversible hydration of carbon dioxide. Its role in saliva is unknown.
Cellular Location Secreted.
Tissue Location Major constituent of saliva.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown.

References

Padiglia, A., et al. Am. J. Clin. Nutr. 92(3):539-545(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Peres, R.C., et al. Pharmacogenomics J. 10(2):114-119(2010)
Nishimori, I., et al. Bioorg. Med. Chem. 15(15):5351-5357(2007)
Breton, S. JOP 2 (4 SUPPL), 159-164 (2001) :

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$ 182.50
$ 70.00
Cat# AP12663b
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