- CITATIONS: 1
|Application ||IHC-P, WB, E|
|Calculated MW||76004 Da|
|Antigen Region||551-579 aa|
|Other Names||Ligand of Numb protein X 2, Numb-binding protein 2, PDZ domain-containing RING finger protein 1, LNX2, PDZRN1|
|Target/Specificity||This LNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the C-terminal region of human LNX2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LNX2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
Provided below are standard protocols that you may find useful for product applications.
LNX2 (Ligand of numb-protein X 2) is a multimodular protein that binds to NUMB via the NPXY motif. It may serve as a molecular scaffold that localizes unrelated, interacting proteins, such as NUMB, to specific subcellular sites.
Thorleifsson, G., et al. Nat. Genet. 41(1):18-24(2009)
Sullivan, P.F., et al. Mol. Psychiatry 13(6):570-584(2008)
Dunham, A., et al. Nature 428(6982):522-528(2004)
Rice, D.S., et al. Mol. Cell. Neurosci. 18(5):525-540(2001)
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