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RAB3D Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | O95716 |
| Other Accession | NP_004274.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 24267 Da |
| Antigen Region | 185-212 aa |
| Gene ID | 9545 |
|---|---|
| Other Names | Ras-related protein Rab-3D, RAB3D, GOV, RAB16 |
| Target/Specificity | This RAB3D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-212 amino acids from the C-terminal region of human RAB3D. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RAB3D Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RAB3D (HGNC:9779) |
|---|---|
| Synonyms | GOV, RAB16 |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB3D may be involved in the insulin-induced exocytosis of GLUT4-containing vesicles in adipocytes (By similarity). |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side |
| Tissue Location | Highly expressed in granulocytes of peripheral blood (PubMed:10023084). Constitutively expressed at low levels in all hematopoietic cell lines investigated (PubMed:10023084) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
RAB3D is a protein transport. Probably involved in regulated exocytosis (By similarity).
References
Tian, X., et al. Mol. Cell. Biol. 30(5):1269-1284(2010)
Knop, M., et al. EMBO J. 23(15):2982-2992(2004)
Matsumoto, M., et al. Proc. Natl. Acad. Sci. U.S.A. 101(22):8313-8318(2004)
Nguyen, D., et al. J. Cell. Physiol. 197(3):400-408(2003)
Fukuda, M. J. Biol. Chem. 278(17):15373-15380(2003)
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