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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   ARMC9 Antibody (N-term)   

ARMC9 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ARMC9 Antibody (N-term) AP13443a
    ARMC9 Antibody (N-term) (Cat. #AP13443a) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ARMC9 antibody detected the ARMC9 protein (arrow).
  • IHC-P - ARMC9 Antibody (N-term) AP13443a
    ARMC9 Antibody (N-term) (Cat. #AP13443a)immunohistochemistry analysis in formalin fixed and paraffin embedded human melanoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ARMC9 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q7Z3E5
Other Accession NP_079415.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 91819 Da
Antigen Region 95-124 aa
Additional Information
Gene ID 80210
Other Names LisH domain-containing protein ARMC9, Melanoma/melanocyte-specific tumor antigen KU-MEL-1, NS21, ARMC9, KIAA1868
Target/Specificity This ARMC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the N-terminal region of human ARMC9.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsARMC9 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARMC9 (HGNC:20730)
Synonyms KIAA1868
Function Acts as a positive regulator of hedgehog (Hh)signaling (By similarity). Involved in ciliogenesis (By similarity). May participate in the trafficking and/or retention of GLI2 and GLI3 proteins at the ciliary tip (By similarity).
Cellular Location Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium {ECO:0000250|UniProtKB:Q9D2I5}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Localized to the proximal region in cilia. Stimulation of Hh signaling leads to redistribution of ARMC9 toward the ciliary tip within 6 hours, follow by a gradual return to its original proximal location (By similarity). Localizes to the daughter centriole of the primary cilium in RPE1 cells (PubMed:28625504) {ECO:0000250|UniProtKB:Q9D2I5, ECO:0000269|PubMed:28625504}
Tissue Location Strongly expressed in most melanomas and melanocytes. Weakly expressed in the testis
Research Areas
Citations (0)

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Background

The specific function of the protein remains unknown.

References

Bailey, S.D., et al. Diabetes Care (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Kiniwa, Y., et al. Cancer Res. 61(21):7900-7907(2001)

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$ 350.00
$ 117.00
Cat# AP13443a
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