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CABP5 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NP86 |
| Other Accession | NP_062829.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 19826 Da |
| Antigen Region | 3-32 aa |
| Gene ID | 56344 |
|---|---|
| Other Names | Calcium-binding protein 5, CaBP5, CABP5, CABP3 |
| Target/Specificity | This CABP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-32 amino acids from the N-terminal region of human CABP5. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CABP5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CABP5 |
|---|---|
| Synonyms | CABP3 |
| Function | Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials (By similarity). Involved in the transmission of light signals (By similarity). May positively regulate neurotransmitter vesicle endocytosis and exocytosis in a salt-dependent manner (By similarity). May play a role in the extension and network organization of neurites (By similarity). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Retina.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The product of this gene belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Expression of this gene is retina-specific. The mouse homolog of this protein has been shown to express in the inner nuclear layer of the retina, suggested its role in neuronal functioning. The specific function of this gene is unknown.
References
Haeseleer, F., et al. Biochem. Biophys. Res. Commun. 290(2):615-623(2002)
Haeseleer, F., et al. J. Biol. Chem. 275(2):1247-1260(2000)
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