PCDH18 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9HCL0 |
Other Accession | NP_061908.1 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 126149 Da |
Antigen Region | 970-999 aa |
Gene ID | 54510 |
---|---|
Other Names | Protocadherin-18, PCDH18, KIAA1562 |
Target/Specificity | This PCDH18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 970-999 amino acids from the C-terminal region of human PCDH18. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PCDH18 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PCDH18 |
---|---|
Synonyms | KIAA1562 |
Function | Potential calcium-dependent cell-adhesion protein. |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in all tissues, with highest expression in lung and ovary. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain.
References
Homayouni, R., et al. Biochem. Biophys. Res. Commun. 289(2):539-547(2001)
Wolverton, T., et al. Genomics 76 (1-3), 66-72 (2001) :
Suzuki, S.T. Exp. Cell Res. 261(1):13-18(2000)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000)
Yagi, T., et al. Genes Dev. 14(10):1169-1180(2000)
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