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PCDH18 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9HCL0 |
| Other Accession | NP_061908.1 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 126149 Da |
| Antigen Region | 970-999 aa |
| Gene ID | 54510 |
|---|---|
| Other Names | Protocadherin-18, PCDH18, KIAA1562 |
| Target/Specificity | This PCDH18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 970-999 amino acids from the C-terminal region of human PCDH18. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PCDH18 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PCDH18 |
|---|---|
| Synonyms | KIAA1562 |
| Function | Potential calcium-dependent cell-adhesion protein. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in all tissues, with highest expression in lung and ovary. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain.
References
Homayouni, R., et al. Biochem. Biophys. Res. Commun. 289(2):539-547(2001)
Wolverton, T., et al. Genomics 76 (1-3), 66-72 (2001) :
Suzuki, S.T. Exp. Cell Res. 261(1):13-18(2000)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000)
Yagi, T., et al. Genes Dev. 14(10):1169-1180(2000)
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