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CNNM4 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CNNM4 Antibody (C-term) AP13590b
    CNNM4 Antibody (C-term) (Cat. #AP13590b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CNNM4 antibody detected the CNNM4 protein (arrow).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q6P4Q7
Other Accession NP_064569.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 86607 Da
Antigen Region 501-530 aa
Additional Information
Gene ID 26504
Other Names Metal transporter CNNM4, Ancient conserved domain-containing protein 4, Cyclin-M4, CNNM4, ACDP4, KIAA1592
Target/Specificity This CNNM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 501-530 amino acids from the C-terminal region of human CNNM4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCNNM4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNNM4
Synonyms ACDP4, KIAA1592
Function Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Widely expressed. Highly expressed in heart.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone-rod dystrophy and amelogenesis imperfecta. [provided by RefSeq].

References

Polok, B., et al. Am. J. Hum. Genet. 84(2):259-265(2009)
Parry, D.A., et al. Am. J. Hum. Genet. 84(2):266-273(2009)
Guo, D., et al. Mol Pain 1, 15 (2005) :
Michaelides, M., et al. J. Med. Genet. 41(6):468-473(2004)
Wang, C.Y., et al. Gene 306, 37-44 (2003) :

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$ 182.50
$ 70.00
Cat# AP13590b
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