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DCBLD2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q96PD2 |
| Other Accession | NP_563615.3 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 85035 Da |
| Antigen Region | 538-567 aa |
| Gene ID | 131566 |
|---|---|
| Other Names | Discoidin, CUB and LCCL domain-containing protein 2, CUB, LCCL and coagulation factor V/VIII-homology domains protein 1, Endothelial and smooth muscle cell-derived neuropilin-like protein, DCBLD2, CLCP1, ESDN |
| Target/Specificity | This DCBLD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 538-567 amino acids from the C-terminal region of human DCBLD2. |
| Dilution | FC~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DCBLD2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DCBLD2 |
|---|---|
| Synonyms | CLCP1, ESDN |
| Cellular Location | Membrane; Single- pass type I membrane protein |
| Tissue Location | Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
DCBLD2, otherwise known as ESDN (endothelial and smooth muscle cell-derived neuropilin-like molecule) is a novel type-I transmembrane protein with the longest cleavable secretory signal sequence among eukaryotes. It is expressed in various tissues; particularly highly expressed in cultured vascular smooth muscle cells. DCBLD2 is considered to play a role in regulation of vascular cell growth and may have a wide variety of functions in other tissues including the nervous system, like neuropilins.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Guo, X., et al. J. Biol. Chem. 284(43):29376-29382(2009)
Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)
Kim, M., et al. Mol. Cancer Res. 6(2):222-230(2008)
Sadeghi, M.M., et al. Am. J. Transplant. 7(9):2098-2105(2007)
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