ACTR6 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9GZN1 |
Other Accession | Q9D864, Q9DEE9, NP_071941.1 |
Reactivity | Human |
Predicted | Chicken, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 45810 Da |
Antigen Region | 346-374 aa |
Gene ID | 64431 |
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Other Names | Actin-related protein 6, hArp6, hARPX, ACTR6 |
Target/Specificity | This ACTR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-374 amino acids from the C-terminal region of human ACTR6. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ACTR6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ACTR6 |
---|---|
Function | Required for formation and/or maintenance of proper nucleolar structure and function (PubMed:26164235). Plays a dual role in the regulation of ribosomal DNA (rDNA) transcription (By similarity). In the presence of high glucose, maintains active rDNA transcription through H2A.Z deposition and under glucose starvation, is required for the repression of rDNA transcription, and this function may be independent of H2A.Z (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P45890}. Nucleus Nucleus, nucleolus. Note=Colocalizes with HP1 family proteins at pericentric heterochromatin |
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Provided below are standard protocols that you may find useful for product applications.
Background
ACTR6 belongs to the actin family.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Ohfuchi, E., et al. Eur. J. Cell Biol. 85(5):411-421(2006)
Kato, M., et al. Gene 268 (1-2), 133-140 (2001) :
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