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NRTN Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - NRTN Antibody (Center) AP14055c
    NRTN Antibody (Center) (Cat. #AP14055c) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NRTN antibody detected the NRTN protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q99748
Other Accession NP_004549.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 22405 Da
Antigen Region 46-75 aa
Additional Information
Gene ID 4902
Other Names Neurturin, NRTN
Target/Specificity This NRTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the Central region of human NRTN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNRTN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRTN
Function Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
Cellular Location Secreted.
Research Areas
Citations (0)
citation

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Background

Neurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq].

References

Fernandez, R.M., et al. J. Pediatr. Surg. 43(11):2042-2047(2008)
Adly, M.A., et al. J. Am. Acad. Dermatol. 58(2):238-250(2008)
Yoong, L.F., et al. J. Neurosci. 27(21):5603-5614(2007)
Yoong, L.F., et al. J. Neurochem. 98(4):1149-1158(2006)
Vargas-Leal, V., et al. J. Immunol. 175(4):2301-2308(2005)

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$ 182.50
$ 70.00
Cat# AP14055c
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