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Mouse Mlk4 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q8VDG6 |
| Other Accession | NP_663583.2 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 110112 Da |
| Antigen Region | 566-593 aa |
| Gene ID | 234878 |
|---|---|
| Other Names | Mitogen-activated protein kinase kinase kinase MLK4, Mixed lineage kinase 4, Mlk4, Kiaa1804 |
| Target/Specificity | This Mouse Mlk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 566-593 amino acids from the Central region of mouse Mlk4. |
| Dilution | IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Mlk4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Map3k21 |
|---|---|
| Synonyms | Kiaa1804, Mlk4 |
| Function | Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways (By similarity). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Mlk4 activates the JUN N-terminal pathway (By similarity).
References
Katayama, S., et al. Science 309(5740):1564-1566(2005)
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