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Mouse Sgk196 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q3TUA9 |
| Other Accession | Q4V8A9, NP_083313.1 |
| Reactivity | Mouse |
| Predicted | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 39969 Da |
| Antigen Region | 245-273 aa |
| Gene ID | 74653 |
|---|---|
| Other Names | Protein O-mannose kinase, POMK, 271-, Protein kinase-like protein SgK196, Sugen kinase 196, Pomk, Sgk196 |
| Target/Specificity | This Mouse Sgk196 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-273 amino acids from the C-terminal region of mouse Sgk196. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Sgk196 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Pomk |
|---|---|
| Synonyms | Sgk196 |
| Function | Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)- beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4- (phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O- mannose, suggesting that this disaccharide serves as the substrate recognition motif (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type II membrane protein |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
References
Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)
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$ 385.00
$ 150.00
Cat# AP14296b
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