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PIPPIN Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9Y534 |
| Other Accession | Q63430, Q91YQ3, NP_055275.1 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 16786 Da |
| Antigen Region | 76-105 aa |
| Gene ID | 27254 |
|---|---|
| Other Names | Cold shock domain-containing protein C2, RNA-binding protein PIPPin, CSDC2, PIPPIN |
| Target/Specificity | This PIPPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human PIPPIN. |
| Dilution | IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PIPPIN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CSDC2 |
|---|---|
| Synonyms | PIPPIN |
| Function | RNA-binding factor which binds specifically to the very 3'- UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity). |
| Cellular Location | Nucleus. Cytoplasm. Note=PIPPin-RNA complexes are located to the nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity).
References
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Schafer, C., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 285 (4), G726-G734 (2003) :
Raimondi, L., et al. J. Cell. Mol. Med. 7(1):35-42(2003)
Nastasi, T., et al. Neuroreport 11(10):2233-2236(2000)
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