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PPEF1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O14829 |
| Other Accession | NP_006231.2, NP_689410.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 75792 Da |
| Antigen Region | 298-327 aa |
| Gene ID | 5475 |
|---|---|
| Other Names | Serine/threonine-protein phosphatase with EF-hands 1, PPEF-1, Protein phosphatase with EF calcium-binding domain, PPEF, Serine/threonine-protein phosphatase 7, PP7, PPEF1, PPEF, PPP7C |
| Target/Specificity | This PPEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-327 amino acids from the Central region of human PPEF1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PPEF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PPEF1 |
|---|---|
| Synonyms | PPEF, PPP7C |
| Function | May have a role in the recovery or adaptation response of photoreceptors. May have a role in development. |
| Tissue Location | Detected in retina and retinal derived Y-79 retinoblastoma cells. Also found in fetal brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described.
References
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) :
Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)
Kutuzov, M.A., et al. Biochem. Biophys. Res. Commun. 293(3):1047-1052(2002)
Ramulu, P., et al. Mol. Cell. Biol. 21(24):8605-8614(2001)
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