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CSDA Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P16989 |
| Other Accession | Q62764, Q9JKB3, NP_001138898.1, NP_003642.3 |
| Reactivity | Human, Mouse |
| Predicted | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 40090 Da |
| Antigen Region | 152-181 aa |
| Gene ID | 8531 |
|---|---|
| Other Names | Y-box-binding protein 3, Cold shock domain-containing protein A, DNA-binding protein A, Single-strand DNA-binding protein NF-GMB, YBX3, CSDA, DBPA |
| Target/Specificity | This CSDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-181 amino acids from the Central region of human CSDA. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CSDA Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | YBX3 |
|---|---|
| Synonyms | CSDA, DBPA |
| Function | Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full-length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity). |
| Cellular Location | Cytoplasm. Nucleus. |
| Tissue Location | Highly expressed in skeletal muscle and heart. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CSDA binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity).
References
Lima, W.R., et al. J. Am. Soc. Nephrol. 21(3):478-488(2010)
Wang, G.R., et al. Acta Pharmacol. Sin. 30(10):1436-1442(2009)
Sharpe Elles, L.M., et al. Nucleic Acids Res. 37(19):6503-6514(2009)
Buchert, M., et al. Gastroenterology 137(1):156-164(2009)
Hayashi, J., et al. Int. J. Oncol. 21(4):847-850(2002)
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