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SDC3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O75056 |
| Other Accession | P33671, Q64519, NP_055469.3 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 45497 Da |
| Antigen Region | 413-442 aa |
| Gene ID | 9672 |
|---|---|
| Other Names | Syndecan-3, SYND3, SDC3, KIAA0468 |
| Target/Specificity | This SDC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-442 amino acids from the C-terminal region of human SDC3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SDC3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SDC3 |
|---|---|
| Synonyms | KIAA0468 |
| Function | Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in the nervous system, the adrenal gland, and the spleen. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity.
References
Schuring, A.N., et al. J. Mol. Med. 87(12):1241-1250(2009)
Marzioni, D., et al. Int J Immunopathol Pharmacol 22(3):627-638(2009)
Yao, J., et al. Dig. Dis. Sci. 54(4):895-901(2009)
Landgraf, P., et al. J. Biol. Chem. 283(36):25036-25045(2008)
Dews, I.C., et al. Proc. Natl. Acad. Sci. U.S.A. 104(52):20782-20787(2007)
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