PBX2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, E |
---|---|
Primary Accession | P40425 |
Other Accession | O35984, NP_002577.2 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 45881 Da |
Antigen Region | 181-210 aa |
Gene ID | 5089 |
---|---|
Other Names | Pre-B-cell leukemia transcription factor 2, Homeobox protein PBX2, Protein G17, PBX2, G17 |
Target/Specificity | This PBX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from the Central region of human PBX2. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PBX2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PBX2 |
---|---|
Synonyms | G17 |
Function | Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1. |
Cellular Location | Nucleus. |
Tissue Location | Ubiquitously expressed. |

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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6. [provided by RefSeq].
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
Qiu, Y., et al. Int. J. Oncol. 36(3):651-663(2010)
Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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