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MSGN1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | A6NI15 |
| Other Accession | NP_001099039.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 20778 Da |
| Antigen Region | 97-125 aa |
| Gene ID | 343930 |
|---|---|
| Other Names | Mesogenin-1, Paraxial mesoderm-specific mesogenin1, pMesogenin1, pMsgn1, MSGN1 |
| Target/Specificity | This MSGN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-125 amino acids from the Central region of human MSGN1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MSGN1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MSGN1 |
|---|---|
| Function | Involved in specifying the paraxial, but not dorsal, mesoderm. May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
MSGN1 is involved in the formation and segmentation of paraxial mesoderm. Has the regulatory capacity to specify ventrolateral (including future paraxial), but not dorsal (future axial), mesoderm phenotypes. Seems to be an upstream regulator of at least some elements of the Notch and Delta signaling pathway (By similarity).
References
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
Yoon, J.K., et al. Dev. Biol. 222(2):376-391(2000)
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