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HSF5 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q4G112 |
| Other Accession | NP_001073908.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 65265 Da |
| Antigen Region | 542-571 aa |
| Gene ID | 124535 |
|---|---|
| Other Names | Heat shock factor protein 5, HSF 5, Heat shock transcription factor 5, HSTF 5, HSF5, HSTF5 |
| Target/Specificity | This HSF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542-571 amino acids from the C-terminal region of human HSF5. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HSF5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HSF5 |
|---|---|
| Synonyms | HSTF5 |
| Function | DNA-binding transcription factor that is essential for male fertility, spermatogenesis and meiotic prophase progression in spermatocytes under non-stress conditions. Positvely and negatively regulates gene expression to ensure progression of meiotic prophase beyond pachytene stage in spermatocytes. Plays a role in male germline meiotic sex chromosome remodeling and silencing through regulation of SMARCA4. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q5ND04}. Chromosome {ECO:0000250|UniProtKB:Q5ND04}. Note=Expressed primarily in the XY body of pachytene spermatocytes. {ECO:0000250|UniProtKB:Q5ND04} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
HSF5 may act as a transcriptional factor (By similarity).
References
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
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