HSF5 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P, IHC-F, IF, ICC, E |
---|---|
Primary Accession | Q4G112 |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 65265 Da |
Gene ID | 124535 |
---|---|
Other Names | Heat shock factor protein 5, HSF 5, Heat shock transcription factor 5, HSTF 5, HSF5, HSTF5 |
Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | HSF5 |
---|---|
Synonyms | HSTF5 |
Function | DNA-binding transcription factor that is essential for male fertility, spermatogenesis and meiotic prophase progression in spermatocytes under non-stress conditions. Positvely and negatively regulates gene expression to ensure progression of meiotic prophase beyond pachytene stage in spermatocytes. Plays a role in male germline meiotic sex chromosome remodeling and silencing through regulation of SMARCA4. |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q5ND04}. Chromosome {ECO:0000250|UniProtKB:Q5ND04}. Note=Expressed primarily in the XY body of pachytene spermatocytes. {ECO:0000250|UniProtKB:Q5ND04} |

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