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MYT1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q01538 |
| Other Accession | NP_004526.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 122329 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 4661 |
|---|---|
| Other Names | Myelin transcription factor 1, MyT1, Myelin transcription factor I, MyTI, PLPB1, Proteolipid protein-binding protein, MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1 |
| Target/Specificity | This MYT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MYT1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MYT1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MYT1 |
|---|---|
| Synonyms | KIAA0835, KIAA1050, MTF1, MYTI, PLPB1 |
| Function | Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription. |
| Cellular Location | Nucleus. |
| Tissue Location | Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
MYT1 is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.
References
Choi, H.S., et al. Mol. Cell. Biol. 29(8):2168-2180(2009)
Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)
Vana, A.C., et al. Glia 55(7):687-697(2007)
Nielsen, J.A., et al. Mol. Cell. Neurosci. 25(1):111-123(2004)
Nakajima, H., et al. J. Biol. Chem. 278(28):25277-25280(2003)
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