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SLITRK2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9H156 |
| Other Accession | Q810C0, NP_115928.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 95404 Da |
| Antigen Region | 773-801 aa |
| Gene ID | 84631 |
|---|---|
| Other Names | SLIT and NTRK-like protein 2, SLITRK2, CXorf2, KIAA1854, SLITL1 |
| Target/Specificity | This SLITRK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 773-801 amino acids from the C-terminal region of human SLITRK2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SLITRK2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLITRK2 |
|---|---|
| Synonyms | CXorf2, KIAA1854, SLITL1 |
| Function | It is involved in synaptogenesis and promotes excitatory synapse differentiation (PubMed:27273464, PubMed:27812321, PubMed:35840571). Suppresses neurite outgrowth (By similarity). Involved in the negative regulation of NTRK2 (PubMed:35840571). |
| Cellular Location | Membrane; Single-pass type I membrane protein. Cell membrane. Cell projection, dendrite |
| Tissue Location | Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an integral membrane protein that contains two N-terminal leucine-rich repeats domains and contains C-terminal regions similar to neurotrophin receptors. The encoded protein may play a role in modulating neurite activity. Alternatively spliced transcript variants encoding the same protein have been described.
References
Piton, A., et al. Mol. Psychiatry (2010) In press :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Smith, E.N., et al. Mol. Psychiatry 14(8):755-763(2009)
Aruga, J., et al. Gene 315, 87-94 (2003) :
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