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MS4A7 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - MS4A7 Antibody (Center) AP16946c
    MS4A7 Antibody (Center) (Cat. #AP16946c) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MS4A7 antibody detected the MS4A7 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9GZW8
Other Accession NP_996821.1, NP_996823.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 26131 Da
Antigen Region 137-164 aa
Additional Information
Gene ID 58475
Other Names Membrane-spanning 4-domains subfamily A member 7, CD20 antigen-like 4, CD20/FC-epsilon-RI-beta family member 4, Four-span transmembrane protein 2, MS4A7, 4SPAN2, CD20L4, CFFM4
Target/Specificity This MS4A7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-164 amino acids from the Central region of human MS4A7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMS4A7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MS4A7
Synonyms 4SPAN2, CD20L4, CFFM4
Function May be involved in signal transduction as a component of a multimeric receptor complex.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Ubiquitous expression in normal tissues. Expression is more elevated in adult liver, lung, spleen, and heart than in their fetal counterparts, and is higher in normal tissues than in the cancerous tissue or cell lines. Low levels of expression were detected in the promonocytic stage, whereas high levels of expression were detected in mature monocytes
Research Areas
Citations (0)
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Background

This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq].

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Gingras, M.C., et al. Immunogenetics 53(6):468-476(2001)
Liang, Y., et al. Immunogenetics 53(5):357-368(2001)
Liang, Y., et al. Genomics 72(2):119-127(2001)
Ishibashi, K., et al. Gene 264(1):87-93(2001)

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$ 182.50
$ 70.00
Cat# AP16946c
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