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SCAND1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P57086 |
| Other Accession | NP_057642.1, NP_361012.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 19082 Da |
| Antigen Region | 150-179 aa |
| Gene ID | 51282 |
|---|---|
| Other Names | SCAN domain-containing protein 1, SCAND1, SDP1 |
| Target/Specificity | This SCAND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-179 amino acids from the C-terminal region of human SCAND1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SCAND1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SCAND1 |
|---|---|
| Synonyms | SDP1 |
| Function | May regulate transcriptional activity. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. Functional studies have established that the SCAN box is a protein interaction domain that mediates both hetero- and homoprotein associations, and maybe involved in regulation of transcriptional activity. Two transcript variants with different 5' UTRs, but encoding the same protein, have been described for this gene.
References
Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
Carneiro, F.R., et al. Biochem. Biophys. Res. Commun. 343(1):260-268(2006)
Babb, R., et al. Biochem. J. 370 (PT 2), 719-727 (2003) :
Sander, T.L., et al. Gene 296 (1-2), 53-64 (2002) :
Deloukas, P., et al. Nature 414(6866):865-871(2001)
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