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CABP4 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CABP4 Antibody (C-term) AP17350b
    CABP4 Antibody (C-term) (Cat. #AP17350b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CABP4 antibody detected the CABP4 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P57796
Other Accession NP_660201.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 30433 Da
Antigen Region 175-203 aa
Additional Information
Gene ID 57010
Other Names Calcium-binding protein 4, CaBP4, CABP4
Target/Specificity This CABP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-203 amino acids from the C-terminal region of human CABP4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCABP4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CABP4
Function Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages (By similarity).
Cellular Location Cytoplasm. Presynapse {ECO:0000250|UniProtKB:Q8VHC5}. Note=Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors {ECO:0000250|UniProtKB:Q8VHC5}
Tissue Location Expressed in retina and in the inner hair cells (IHC) of the cochlea
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the CABP family of calcium binding protein characterized by four EF-hand motifs. Mutations in this gene are associated with congenital stationary night blindness type 2B.

References

Aldahmesh, M.A., et al. Mol. Vis. 16, 207-212 (2010) :
Littink, K.W., et al. Invest. Ophthalmol. Vis. Sci. 50(5):2344-2350(2009)
Zeitz, C., et al. Am. J. Hum. Genet. 79(4):657-667(2006)
Taylor, T.D., et al. Nature 440(7083):497-500(2006)
Haeseleer, F., et al. Nat. Neurosci. 7(10):1079-1087(2004)

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$ 182.50
$ 70.00
Cat# AP17350b
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