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PGM5 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q15124 |
| Other Accession | NP_068800.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 62225 Da |
| Antigen Region | 404-430 aa |
| Gene ID | 5239 |
|---|---|
| Other Names | Phosphoglucomutase-like protein 5, Aciculin, Phosphoglucomutase-related protein, PGM-RP, PGM5, PGMRP |
| Target/Specificity | This PGM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-430 amino acids from the C-terminal region of human PGM5. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PGM5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PGM5 (HGNC:8908) |
|---|---|
| Synonyms | PGMRP |
| Function | Component of adherens-type cell-cell and cell-matrix junctions (PubMed:8175905). Has no phosphoglucomutase activity in vitro (PubMed:8175905). |
| Cellular Location | Cell junction, adherens junction. Cytoplasm, cytoskeleton. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q8BZF8}. Note=Concentrated in focal contacts at the ends of actin bundles, and associated with actin filaments |
| Tissue Location | Detected in smooth and cardiac muscle at high levels and in skeletal muscle at low level. Present in other tissues due to vascular or other smooth muscle component. Low levels are present in liver, kidney, skin and brain (at protein level) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphoglucomutases (EC 5.2.2.2.), such as PGM5, are phosphotransferases involved in interconversion of glucose-1-phosphate and glucose-6-phosphate. PGM activity is essential in formation of carbohydrates from glucose-6-phosphate and in formation of glucose-6-phosphate from galactose and glycogen (Edwards et al., 1995 [PubMed 8586438]).
References
Wakayama, Y., et al. Acta Neuropathol. 99(6):654-662(2000)
Moiseeva, E.P., et al. Eur. J. Biochem. 248(3):634-643(1997)
Moiseeva, E.P., et al. Eur. J. Biochem. 235 (1-2), 103-113 (1996) :
Edwards, Y.H., et al. Genomics 30(2):350-353(1995)
Belkin, A.M., et al. Exp. Cell Res. 221(1):132-140(1995)
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