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NKX3-2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P78367 |
| Other Accession | P70061, P97503, NP_001180.1 |
| Reactivity | Human |
| Predicted | Mouse, Xenopus |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 34814 Da |
| Antigen Region | 3-2 aa |
| Gene ID | 579 |
|---|---|
| Other Names | Homeobox protein Nkx-32, Bagpipe homeobox protein homolog 1, Homeobox protein NK-3 homolog B, NKX3-2, BAPX1, NKX3B |
| Target/Specificity | This NKX3-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-235 amino acids from the Central region of human NKX3-2. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NKX3-2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NKX3-2 |
|---|---|
| Synonyms | BAPX1, NKX3B |
| Function | Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the NK family of homeobox-containing proteins. The encoded protein may play a role in skeletal development.
References
Hellemans, J., et al. Am. J. Hum. Genet. 85(6):916-922(2009)
Rodrigo, I., et al. Mol. Cell. Biol. 24(7):2757-2766(2004)
Tribioli, C., et al. Gene 203(2):225-233(1997)
Yoshiura, K.I., et al. Genomics 45(2):425-428(1997)
Tribioli, C., et al. Mech. Dev. 65 (1-2), 145-162 (1997) :
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