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TEX2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IWB9 |
| Other Accession | NP_060939.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 125303 Da |
| Antigen Region | 571-599 aa |
| Gene ID | 55852 |
|---|---|
| Other Names | Testis-expressed sequence 2 protein, Transmembrane protein 96, TEX2, KIAA1738, TMEM96 |
| Target/Specificity | This TEX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-599 amino acids from the Central region of human TEX2. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TEX2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TEX2 |
|---|---|
| Synonyms | KIAA1738, TMEM96 |
| Function | During endoplasmic reticulum (ER) stress or when cellular ceramide levels increase, may induce contacts between the ER and medial-Golgi complex to facilitate non-vesicular transport of ceramides from the ER to the Golgi complex where they are converted to complex sphingolipids, preventing toxic ceramide accumulation. |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q06833}; Multi-pass membrane protein. Nucleus membrane {ECO:0000250|UniProtKB:Q06833}; Multi- pass membrane protein. Note=Enriched at the nucleus- vacuole junction (PubMed:22250200). During endoplasmic reticulum (ER) stress, localizes to ER-Golgi contacts (By similarity) {ECO:0000250|UniProtKB:Q06833, ECO:0000269|PubMed:22250200} |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
There are two isoforms.
References
Lee, I., et al. FASEB J. 20(2):202-206(2006)
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$ 150.00
$ 385.00
Cat# AP17935c
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