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BTG4 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NY30 |
| Other Accession | NP_060059.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 25970 Da |
| Antigen Region | 142-169 aa |
| Gene ID | 54766 |
|---|---|
| Other Names | Protein BTG4, BTG family member 4, Protein PC3b, BTG4, PC3B |
| Target/Specificity | This BTG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the C-terminal region of human BTG4. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BTG4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BTG4 |
|---|---|
| Synonyms | PC3B |
| Function | Adapter protein that bridges CNOT7, a catalytic subunit of the CCR4-NOT complex, to EIF4E (By similarity). Facilitates maternal mRNAs decay during the maturation of oocytes and in the fertilized egg, and is required for the maternal-zygotic transition (MZT), zygotic cleavage and initiation of embryonic development (PubMed:32502391). |
| Tissue Location | Expressed in oocytes after germinal vesicle breakdown (PubMed:32502391). Expressed in testis and in olfactory epithelium. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein can induce G1 arrest in the cell cycle.
References
Xu, Y., et al. Int. J. Cancer (2010) In press :
Dong, W., et al. Biochem. Biophys. Res. Commun. 387(1):132-138(2009)
Toyota, M., et al. Cancer Res. 68(11):4123-4132(2008)
Auer, R.L., et al. Genes Chromosomes Cancer 43(1):1-10(2005)
Yoshida, Y., et al. Jpn. J. Cancer Res. 92(6):592-596(2001)
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