Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
LDOC1L Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6ICC9 |
| Other Accession | NP_115663.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26154 Da |
| Antigen Region | 160-186 aa |
| Gene ID | 84247 |
|---|---|
| Other Names | Protein LDOC1L, Leucine zipper protein down-regulated in cancer cells-like, Mammalian retrotransposon-derived protein 6, LDOC1L, MAR6, MART6 |
| Target/Specificity | This LDOC1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-186 amino acids from the C-terminal region of human LDOC1L. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LDOC1L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RTL6 (HGNC:13343) |
|---|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
LDOC1 (Leucine zipper protein downregulated in cancer cells) is a 146 amino acid nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kB (NF-kB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. LDOC1L (Leucine zipper protein down-regulated in cancer cells-like), also known as MART6 (Mammalian retrotransposon-derived protein 6), is a 239 amino acid protein that belongs to the LDOC1 family.
References
Brandt, J., et al. Gene 345(1):101-111(2005)
Brandt, J., et al. Cytogenet. Genome Res. 110 (1-4), 307-317 (2005) :
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Shipping Information
