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> home > Products > Primary Antibodies > Antibody Collections > Catalog Updated > IFI44L Antibody (C-term)
IFI44L Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q53G44 |
| Other Accession | NP_006811.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 51322 Da |
| Antigen Region | 151-180 aa |
| Gene ID | 10964 |
|---|---|
| Other Names | Interferon-induced protein 44-like, IFI44L, C1orf29 |
| Target/Specificity | This IFI44L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acid positions 151-180 of human IFI44L. |
| Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | IFI44L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IFI44L |
|---|---|
| Synonyms | C1orf29 |
| Function | Type I interferon-stimulated gene (ISG) that plays a critical role in antiviral and antibacterial activity (PubMed:34722780). During bacterial infection, promotes macrophage differentiation and facilitates inflammatory cytokine secretion (PubMed:34722780). Plays a role in the control of respiratory syncytial virus/RSV infection, reducing the ability of the virus to replicate (PubMed:32611756). Exhibits a low antiviral activity against hepatitis C virus (PubMed:21478870). Also acts as a feedback regulator of IFN responses by negatively regulating IKBKB and IKBKE kinase activities through interaction with FKBP5 (PubMed:31434731). |
| Cellular Location | Cytoplasm. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
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$ 150.00
$ 385.00
Cat# AP18801b
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