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DRG2 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - DRG2 Antibody (Center) AP19144c
    DRG2 Antibody (Center) (Cat. #AP19144c) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the DRG2 antibody detected the DRG2 protein (arrow).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P55039
Other Accession Q9QXB9, Q58D56, NP_001379.1
Reactivity Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 40746 Da
Antigen Region 154-180 aa
Additional Information
Gene ID 1819
Other Names Developmentally-regulated GTP-binding protein 2, DRG-2, DRG2
Target/Specificity This DRG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-180 amino acids from the Central region of human DRG2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDRG2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DRG2 {ECO:0000303|PubMed:29915238, ECO:0000312|HGNC:HGNC:3030}
Function Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.
Cellular Location Nucleus. Cytoplasm
Tissue Location Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes
Research Areas
Citations (0)
citation

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Background

The DRG2 gene encodes the developmentally regulated GTP-binding protein 2, a name derived from the fact that it shares significant similarity to known GTP-binding proteins. DRG2 was identified because it is expressed in normal fibroblasts but not in SV40-transformed fibroblasts. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq].

References

Song, H., et al. J. Biochem. 135(3):331-335(2004)
Bi, W., et al. Genome Res. 12(5):713-728(2002)
Li, B., et al. Biochim. Biophys. Acta 1491 (1-3), 196-204 (2000) :
Vlangos, C.N., et al. Cytogenet. Cell Genet. 88 (3-4), 283-285 (2000) :
Liang, Y., et al. Genomics 61(3):243-258(1999)

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$ 365.00
$ 140.00
Cat# AP19144c
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