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DNER Antibody(C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8NFT8 |
| Other Accession | Q8JZM4, NP_620711.3 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 78475 Da |
| Antigen Region | 708-736 aa |
| Gene ID | 92737 |
|---|---|
| Other Names | Delta and Notch-like epidermal growth factor-related receptor, DNER, BET |
| Target/Specificity | This DNER antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 708-736 amino acids from the C-terminal region of human DNER. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DNER Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DNER |
|---|---|
| Synonyms | BET |
| Function | Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Note=Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity). |
| Tissue Location | Expressed in brain, spinal cord and adrenal gland. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity).
References
Kurisu, J., et al. J. Neurochem. 113(6):1598-1610(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Park, J.R., et al. Cell Prolif. 43(1):19-28(2010)
Ramachandran, P., et al. J. Proteome Res. 5(6):1493-1503(2006)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
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