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UBR7 Antibody(N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - UBR7 Antibody(N-term) AP19480a
    UBR7 Antibody (N-term) (Cat. #AP19480a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the UBR7 antibody detected the UBR7 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8N806
Other Accession NP_001093887.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 47999 Da
Antigen Region 100-128 aa
Additional Information
Gene ID 55148
Other Names Putative E3 ubiquitin-protein ligase UBR7, 632-, N-recognin-7, UBR7, C14orf130
Target/Specificity This UBR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the N-terminal region of human UBR7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUBR7 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBR7
Synonyms C14orf130
Function E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Tissue Location Expressed in sperm (at protein level).
Research Areas
Citations (0)
citation

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Background

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity).

References

Lee, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(1):100-105(2008)
Lim, J., et al. Cell 125(4):801-814(2006)

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$ 365.00
$ 140.00
Cat# AP19480a
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