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UBR7 Antibody(N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8N806 |
| Other Accession | NP_001093887.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 47999 Da |
| Antigen Region | 100-128 aa |
| Gene ID | 55148 |
|---|---|
| Other Names | Putative E3 ubiquitin-protein ligase UBR7, 632-, N-recognin-7, UBR7, C14orf130 |
| Target/Specificity | This UBR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the N-terminal region of human UBR7. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UBR7 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UBR7 |
|---|---|
| Synonyms | C14orf130 |
| Function | E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. |
| Tissue Location | Expressed in sperm (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity).
References
Lee, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(1):100-105(2008)
Lim, J., et al. Cell 125(4):801-814(2006)
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