Mouse Lrmp Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q60664 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 59588 Da |
| Antigen Region | 403-431 aa |
| Gene ID | 16970 |
|---|---|
| Other Names | Lymphoid-restricted membrane protein, Protein Jaw1, Processed lymphoid-restricted membrane protein, Lrmp, Jaw1 |
| Target/Specificity | This Mouse Lrmp antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 403-431 amino acids from the C-terminal region of mouse Lrmp. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Lrmp Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Irag2 |
|---|---|
| Function | Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion (PubMed:9314557). Plays a role in maintaining nuclear shape, maybe as a component of the LINC complex and through interaction with microtubules (PubMed:29878215). Plays a role in the regulation of cellular excitability by regulating the hyperpolarization-activated cyclic nucleotide-gated HCN4 channel activity (PubMed:32647060). |
| Cellular Location | [Processed inositol 1,4,5-triphosphate receptor associated 2]: Cytoplasm |
| Tissue Location | Spleen and thymus. Expressed at high levels in pre B-cells, mature B-cells and pre T-cells. Expressed at low levels in mature T-cells and plasma B-cells. Expressed in circumvallate (CV), foliate (FL) and fungiform (FF) taste papillae cells of the tongue epithelium. |

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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein is unknown.
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