|Application ||WB, E|
|Calculated MW||31222 Da|
|Antigen Region||261-288 aa|
|Other Names||Protein sprouty homolog 3, Spry-3, SPRY3|
|Target/Specificity||This SPRY3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-288 amino acids from the C-terminal region of human SPRY3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SPRY3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor)|
|Tissue Location||Widely expressed; particularly in the fetal tissues|
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May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
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