RFPL3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | O75679 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 35386 Da |
Antigen Region | 70-98 aa |
Gene ID | 10738 |
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Other Names | Ret finger protein-like 3, RFPL3 |
Target/Specificity | This RFPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human RFPL3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | RFPL3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RFPL3 |
---|---|
Function | (Microbial infection) Stimulates the activity of Human Immunodeficiency Virus 1/HIV-1 pre-integration complex. |
Cellular Location | Cytoplasm. Nucleus. Note=A higher concentration of RFPL3 is observed in the cytoplasm compared to the nucleus |
Tissue Location | Expressed during neurogenesis in differentiating human embryonic stem cells and in the developing human neocortex |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown. RFPL3 protein is encoded by 2 exons and is 91 to 94% identical to RFPL1 and RFPL2. Exon 1 of RFPL3 encodes a putative RING-like motif, and exon 2 encodes a B30-2 domain. Seroussi et al. (1999) proposed that RFPL3 arose from an intrachromosomal duplication.
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