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RFPL3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O75679 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35386 Da |
| Antigen Region | 70-98 aa |
| Gene ID | 10738 |
|---|---|
| Other Names | Ret finger protein-like 3, RFPL3 |
| Target/Specificity | This RFPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human RFPL3. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RFPL3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RFPL3 |
|---|---|
| Function | (Microbial infection) Stimulates the activity of Human Immunodeficiency Virus 1/HIV-1 pre-integration complex. |
| Cellular Location | Cytoplasm. Nucleus. Note=A higher concentration of RFPL3 is observed in the cytoplasm compared to the nucleus |
| Tissue Location | Expressed during neurogenesis in differentiating human embryonic stem cells and in the developing human neocortex |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown. RFPL3 protein is encoded by 2 exons and is 91 to 94% identical to RFPL1 and RFPL2. Exon 1 of RFPL3 encodes a putative RING-like motif, and exon 2 encodes a B30-2 domain. Seroussi et al. (1999) proposed that RFPL3 arose from an intrachromosomal duplication.
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