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FAM26F Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q5R3K3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 34458 Da |
| Antigen Region | 266-295 aa |
| Gene ID | 441168 |
|---|---|
| Other Names | Protein FAM26F, FAM26F, C6orf187 |
| Target/Specificity | This FAM26F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the C-terminal region of human FAM26F. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FAM26F Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CALHM6 (HGNC:33391) |
|---|---|
| Synonyms | C6orf187, FAM26F |
| Function | Pore-forming subunit of an ATP-permeable channel (By similarity). In response to pathogen-derived and proinflammatory stimuli, relocates from intracellular compartments to NK-dendritic cell and NK-macrophage immune synapses where it mediates ATP efflux and NK cell activation involved in antimicrobial and antitumor responses (By similarity). May assemble to form gap junction channel-like structures with gating and ion conductance likely regulated by membrane lipids and voltage rather than by extracellular calcium levels (PubMed:32374262). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Note=Recruited at immune synapses in response to pathogen-derived and proinflammatory stimuli {ECO:0000250|UniProtKB:Q8C9E8} |
| Tissue Location | Placenta.. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Belongs to the FAM26 family.
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$ 192.50
$ 75.00
Cat# AP20331b
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