POMP Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9Y244 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 15789 Da |
Antigen Region | 105-131 aa |
Gene ID | 51371 |
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Other Names | Proteasome maturation protein, Proteassemblin, Protein UMP1 homolog, hUMP1, Voltage-gated K channel beta subunit 41, POMP, C13orf12, UMP1 |
Target/Specificity | This POMP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-131 amino acids from the C-terminal region of human POMP. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | POMP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | POMP |
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Synonyms | C13orf12, UMP1 |
Function | Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation. Mediates the association of 20S preproteasome with the endoplasmic reticulum. |
Cellular Location | Cytoplasm, cytosol. Nucleus. Microsome membrane. |
Tissue Location | Strongly expressed from the basal layer to the granular layer of healthy epidermis, whereas in KLICK patients there is a gradual decrease of expression toward the granular layer |
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Provided below are standard protocols that you may find useful for product applications.
Background
Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation. Mediates the association of 20S preproteasome with the endoplasmic reticulum.
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