|Application ||WB, E|
|Calculated MW||48487 Da|
|Antigen Region||377-401 aa|
|Other Names||Keratin, type I cytoskeletal 20, Cytokeratin-20, CK-20, Keratin-20, K20, Protein IT, KRT20|
|Target/Specificity||This KRT20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-401 amino acids from the C-terminal region of human KRT20.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KRT20 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).|
|Tissue Location||Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
Moll R., et al. Differentiation 53:75-93(1993).
Ota T., et al. Nat. Genet. 36:40-45(2004).
Zhou Q., et al. J. Biol. Chem. 281:16453-16461(2006).
Calnek D., et al. Differentiation 53:95-104(1993).
Moll R., et al. J. Cell Biol. 111:567-580(1990).
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